Connect with us

Hi, what are you looking for?

[t4b-ticker]

World

Covid-19 Vaccinated Pregnant Women Pass High Level Of Antibodies To Babies: Study

The research team led by NYU Grossman School of Medicine in the US found that 100 per cent of the infants had protective antibodies at birth.

Alicja Jakubowska, head nurse of the Central Clinical Hospital of the Ministry of the Interior (MSWiA), receives coronavirus vaccination in Warsaw, Poland, Dec. 27, 2020. (Xinhua Photo)

Washington: Women who receive the mRNA Covid-19 vaccine during pregnancy pass high levels of antibodies to their babies, according to a study. The effectiveness of Covid-19 vaccines lies in their ability to trigger the production of the right antibodies, blood proteins capable of protecting individuals from infection, researchers said. Whether this protection could pass from mothers to their infants before birth had remained a question, they said.

The study, published in the American Journal of Obstetrics & Gynecology Maternal-Fetal Medicine on Wednesday, was conducted on 36 newborns whose mothers received either the Pfizer or Moderna Covid-19 vaccine during pregnancy.

The research team led by NYU Grossman School of Medicine in the US found that 100 per cent of the infants had protective antibodies at birth. Antibodies can either be produced as part of the natural response to infection or triggered by vaccines.

ALSO READ: Long Covid: Double Vaccination Halves Risk Of Developing Long-Lasting Symptoms

Though the sample size is small, ”it is encouraging that neonatal antibody levels are high if women are vaccinated,” said Jennifer L Lighter, an associate professor at Hassenfeld Children’s Hospital at NYU Langone, and the study’s senior author.

The team was able to tell apart antibodies in the neonatal blood that were created in response to natural infection from those made in response to the vaccines. The researchers noted that the result is relevant because natural antibody responses against the SARS-CoV-2 virus, that causes Covid-19, are not sufficiently protective for many people.

Advertisement. Scroll to continue reading.

Recent data from the US Centers for Disease Control and Prevention (CDC) suggests that just 23 per cent of pregnant women have been vaccinated, despite growing evidence of prenatal vaccine safety. The researchers observed the highest levels of antibodies in cord blood of mothers who were fully vaccinated during the second half of their pregnancies.

This insight provides evidence of transferred immunity to neonates, which correlates to protection against infection for infants during the first months of life, they said. ”Studies continue to reinforce the importance of vaccines during pregnancy and their power to protect two lives at once by preventing severe illness in both mothers and babies,” said Ashley S Roman, Professor at NYU Langone Health, and one of the study’s principal investigators.

ALSO READ: Vaccination Certificates From All Countries Must Meet ‘Minimum Criteria’, Says UK

”If babies could be born with antibodies, it could protect them in the first several months of their lives, when they are most vulnerable,” Roman said. Roman and colleagues confirmed the strong evidence that the mRNA vaccines are safe during pregnancy in a study published on August 16 in the same journal.

That study found no increased risks during pregnancy, birth complications, or identifiable risks to the fetus among those who received the vaccine. Existing studies analyse antibodies to the spike protein (anti-S IgG) alone, which may be present after natural infection or vaccination, and do not include antibodies to the nucleocapsid protein (anti-N IgG), which is only present following natural infection.

Advertisement. Scroll to continue reading.

Among the 36 samples collected, all had high levels of anti-S IgG. Of those samples, 31 were tested for anti-N IgG and were negative. ”High levels of transplacental antibody transfer are not surprising. It is consistent with what we see with other immunizations,” Lighter said.

”Our findings add to a growing list of important reasons why women should be advised to receive the COVID-19 vaccine during pregnancy for the added benefit of their newborn receiving crucial protection,” he said.

The researchers emphasised that more study is needed to determine how effective the infant antibodies are, how long protection will last, and if vaccination in the second half of pregnancy may confer higher levels of antibody transfer than vaccination earlier in pregnancy.

You May Also Like

India

SRINAGAR, Jammu and Kashmir – Sixty-year-old Dinesh Mondal and his ice cream cart have been a fixture on the streets of Srinagar for decades....

Opinion

Recently, Welhungerhilfe and Concern worldwide, the two globally acknowledged organizations, released the Global Hunger Index (GHI)-2021. The report places India at 101st place amongst...

India

The Samyukta Kisan Morcha, an umbrella body of farmers' unions, said it will hold a peaceful nationwide rail roko protest from 10 am to...

Education

New Delhi: The Central Board of Secondary Education (CBSE) on Monday night announced the dates for Class 10 and 12 term-1 board exams 2021-22....

Advertisement