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Pfizer, Moderna COVID-19 Vaccine Do Not Decrease Fertility, Sperm Count: Study

Andrologist performed several analyses on the samples in accordance with the World Health Organisation’s (WHO) guideline which included semen volume, sperm concentration, sperm motility, and total motile sperm count (TMSC).

COVID-19 Vaccination (PTI Photo)
A health worker administers a dose of a COVID-19 vaccine to a woman, at a Railway hospital in Prayagraj, Friday, June 11, 2021. (PTI Photo)(

New Delhi: A study published in the journal JAMA states that taking the COVID-19 Vaccine does not have any ill effects on male fertility. The study found that male participants did not show any decrease in the amount of sperm that was produced by males who were inoculated with both doses of vaccine from Moderna or Pfizer. 45 healthy male volunteers aged between 18 to 45 participated in the study.

The participants were screened earlier for any fertility issues.

People who showed COVID-19 symptoms or who had returned a positive test in the past 90 days were excluded.

The first semen sample was provided two to seven days before the first vaccine shot while the second shot semen sample was taken 70 days after the second dose.

Andrologists performed several analyses on the samples in accordance with the World Health Organisation’s (WHO) guideline which included semen volume, sperm concentration, sperm motility, and total motile sperm count (TMSC).

“One of the reasons for vaccine hesitancy is the potential negative effect on fertility,” the authors of the study from the University of Miami in the US noted.

“Because reproductive toxicity was not evaluated in the clinical trials and SARS-CoV-2 has been associated with decreases in sperm parameters, we assessed sperm parameters before and after mRNA vaccine administration,” they said.

The study found that before the first dose the TMSC was 36 million while the Sperm Concentration was at 26 million/milliliter (mL).

This increased to 30 million/mL (Sperm Concentration) and 44 million(TMSC) in the second sample.

The researchers said that since the vaccine contained mRNA instead of the live virus it was highly unlikely that the vaccines would have any effect on fertility.

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The researchers also noted that while semen analysis is the foundation of male fertility evaluation, it is an imperfect predictor of fertility potential.

With inputs from PTI

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